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Moreover, we found that colistin-induced depolarization is sensitive to cyclosporin A, a potent inhibitor of mitochondrial cyclophilin D (CyPD), one of the components of the mPTP, whose expression and function are required for the onset of the permeability transition 49

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6 Fifty patients (mean age, 32 years) with episodic migraine were randomly assigned to receive, in double-blind fashion, 100 mg of CoQ10 3 times per day or placebo for 8 weeks

With smaller l-carnitine stores in plasma as compared to omnivores, 12-weeks supplementation with l-carnitine increased both plasma and muscle carnitine, though muscle function and energy metabolism remained unaffected [16]

Current Medicinal Chemistry

doi: 10.1080/07315724.2005.10719462