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Well over 10,000 AR binding sites have been identified in CaP cells, and it has become clear that most AR target genes harbor more than 1 ARE

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10.1136/bcr-2023-259335 61 RenC.WuC.YangC.LianC

An increased susceptibility to sepsis-induced ARDS and lethality 34 was observed in mice lacking the transcription factor Nrf2, which has among its target genes the GSH biosynthetic enzyme gamma-glutamylcysteine synthase

The depletion of GPX4 and GSH, the increased level of lipid peroxidation, and disrupted iron metabolism are vital features of ferroptosis ( Being a novel mode of cell death, ferroptosis is known to be related to tumor progression and therapeutic efficacy

You can think of proteins as a full-length necklace, while peptides are like short strands of that same chain