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A single dose of dietary glycine raises plasma glycine concentration after 10 min 23 , and earlier clinical trials showed that two weeks of dietary glycine supplementation at a similar dose to what was used in this study significantly raised glycine levels in individuals with glycine deficiency from HIV infection 18 , uncontrolled diabetes 17 , and old age 19,24

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Several studies reported that the levels of MDA in plasma were markedly higher in OA patients than in healthy controls [98,99,100]