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Interestingly, the chronological life span (CLS) was lowered in the gsh1 strain cultured with 10% glucose but not under dietary restriction

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L-carnitine is a nutrient that promotes energy production in cells by transporting fatty acids into the mitochondrion, an intracellular structure that generates metabolic energy in the form of atp

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Acetaminophen (APAP)-induced acute liver injury (AILI) is primarily driven by CYP3A4mediated overproduction of the toxic metabolite N-acetyl-p-benzoquinone imine (NAPQI), CYP3A4 activity serves as the rate-limiting determinant of NAPQI accumulation levels

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