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doi: 10.1186/s12906-021-03298-y, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] 50.Variya BC, Bakrania AK, Patel SS

Additionally, other studies have shown that SP1 can be activated at the transcriptional level through HIF-1 binding to its promoter under hypoxic conditions [64, 65]

Tregs themselves are vital in peripheral immune tolerance and suppressing autoimmunity and inflammation through control of adaptive and innate immune responses (Astarita et al., 2023)

10.1046/j.1471-4159.2003.01621.x 148 McCormackA

While the exact immunopathogenesis of DILI is still unclear, its mechanisms may involve direct toxic effects, metabolic disturbances, and both metabolic and allergic idiosyncrasies

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