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Effect of the rate of niacin administration on the plasma and urine pharmacokinetics of niacin and its metabolites

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Discontinue use of NSAIDs and other blood thinning medications for three days prior to administration to help reduce the risk of bruising or bleeding (check with your physician prior to discontinuing prescribed medications)

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Symptoms associated with vitamin B12 deficiency include fatigue and lack of energy (due to anaemia), and depression, psychosis and even dementia