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10.1016/S0944-7113(97)80032-3 12 FeldmanA.AignerE.WeghuberD.PaulmichlK

41 KaltschmidtC.KaltschmidtB.BaeuerleP

Solid-phase peptide synthesis (SPPS) offers numerous advantages over liquid-phase peptide synthesis (LPPS) for the preparation and large-scale manufacturing of synthetic peptides

Compared with standard glutathione (500 mg), LipoMicel at a lower dose (300 mg) increased iAUC and C max by ~2.49-fold and ~2.43-fold, respectively, and when dose-normalized (to a 300 mg equivalent), incremental systemic exposure and peak levels were up to ~4-fold higher, supporting greater absorption per unit dose. The findings indicate LipoMicel is a promising delivery method for oral glutathione, though the researchers added larger, long-term studies are still needed

Chu et al., 2013)

PLoS ONE 11 , e0165125 (2016)