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Antioxidants (Basel) 11, 1374

IGF-1 binding proteins (IGFBPs) are hypothesized to have a role in glucose metabolism, with IGFBP-1 acutely regulating glucose levels through its effects on free IGF-I (24)

More recently the association between CoA metabolism and inflammation has also been suggested as it has been shown that the pantetheinase enzyme that recycles pantothenic acid and pantetheinase gene (vanin-1) knockout mice has been shown to be involved in the progression of inflammatory reactions [16]

Journal of the Medical Association of Thailand (2012)
doi: 10.3390/nu14030644

Seven relevant studies were included in the meta-analysis, which demonstrated that the combination of gabapentin and opioids effectively reduced pain intensity compared to opioids alone [69]