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A catalytic antioxidant (AEOL 10150) attenuates expression of inflammatory genes in stroke

Because glutamine is the source of -KG, glutaminase inhibitors such as BPTES interfere with -KG homeostasis and lead to inhibited proliferation in cancer cells carrying this mutant IDH1 (Seltzer et al., 2010)

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UV radiations can elevate the production of tryptase enzyme in the mast cells

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