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The IV solution was given over 4 min, while the oral one consisted of 317.6 mg trometanlole salt, which corresponded to 200 mg of free ALA, 4 tablets of 50 mg and 1 tablet of 200 mg, given to 12 healthy subjects

But efficacy plateaus above 50mg methionine per dose

ECKH_W10803)

The function of the HCV helicase is not known, but it may be involved in the initiation of RNA synthesis on the HCV genome RNA, which contains stable 3-terminal secondary structure, in dissociation of nascent RNA strands from their template during RNA synthesis, or in displacement of proteins or other trans -acting factors from the RNA genome

2017 Oct;94:124-128

2e and Supplementary Fig