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p=0.007), the primary endpoint, and slowed unconfirmed 1.5-point EDSS progression (-28%

Not sure whether B12 injections are the right call for you

Nov 2020;190:109920

PLoS ONE 9 , e90284 (2014)

[127] [128] Synthesis [edit] Biosynthesis [edit] Vitamin B 12 is derived from a tetrapyrrolic structural framework created by the enzymes deaminase and cosynthetase which transform aminolevulinic acid via porphobilinogen and hydroxymethylbilane to uroporphyrinogen III

In these cases, the solution may be as simple as using vitamin B12 injections rather than taking oral supplements or upping the dosage of B12 in order to achieve its desired effects