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This effectively "rebuilds the highways" of the brain

Hyperpigmentation disorders include melasma, Riehl's melanosis, postinflammation hyperpigmentation (PIH), solar lentigo, and ashy dermatosis [2, 3]

Additionally, shRNA sequences targeting CHAC1 90 or CHAC2 were cloned into a modified version of the doxycycline inducible LT3GEPIR vector 50 , where the puromycin resistance cassette was replaced with a zeocin resistance gene to generate cell lines with temporal control of CHAC1 depletion

Two independent reviewers (K.K.A.C.M

Ross, A

( 1 ) If one primer is designed to span an exon-intron boundary, the possible contaminating genomic DNA is not amplified, because the primer cannot anneal to the template