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Clinically significant vitamin B 12 deficiency and megaloblastic anemia are unlikely, unless these drug therapies are prolonged for two or more years, or if in addition, the person's dietary intake is below recommended levels

Table 2: Patient Risk Factors Associated with Folate Deficiency TOP Prevention Prevention of B 12 Deficiency B 12 is present in many animal products e.g., dairy products, and eggs

The USDA Agricultural Research Service used the 148 pmol/L threshold in their national prevalence studies, and the NIH Office of Dietary Supplements acknowledges that lab reference ranges can vary between institutions

Rather than just tracking weight, DEXA scans or similar body composition measurements would distinguish between fat loss, muscle loss, and water loss

Unexplained hypercobalaminemia, particularly levels above 1,000 pg/mL, has been associated with liver disease, kidney dysfunction, myeloproliferative disorders, and certain solid cancers in multiple large-scale studies