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B12 can enter the small intestine and be absorbed more quickly when the stomach is empty. If B12 upsets your stomach, you can take it with a light meal

And the difference between those doses is the difference between observable results at 12 weeks versus no measurable change

What else could it indicate

Heres why: Energy Production: B12 is essential for converting food into glucose, which provides energy for the body

Pregnant women require adequate levels of folate to prevent neural tube defects in their developing babies

Some studies have incorporated a loading regimen with higher initial doses, followed by lower maintenance doses of 1-2mg per week