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The import of the transcription factor STAT3 into mitochondria depends on GRIM-19, a component of the electron transport chain

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Also, the cyclic AMP-protein kinase signaling pathway that influences the expression and function of nuclear transcription factors such as c-fos, p53, AP-1, Sp1, and CREB (Ca2 + /cAMP response element-binding protein) involved in the transition from proliferation to differentiation of neural cells is impaired by organophosphates (Costa et al., 2008)