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37 HA is a promising novel therapy for PD that appears to have some efficacy in improving PD symptoms, but data comparing HA treatment to placebo or alternative therapies are lacking

In a recent study, the one-year discontinuation rate among newly prescribed patients was notably high, ranging from 91% for tricyclic antidepressants (TCA) to 73.7% for selective serotonin reuptake inhibitor/serotoninnorepinephrine reuptake inhibitor (SSRI/SNRI) antidepressants

doi: 10.1016/j.cpcardiol.2021.100902

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