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Importantly, DNase I digestion, which degrades exosomal dsDNA, markedly suppressed STINGTBK1IRF3 signaling, confirming the functional contribution of exosomal dsDNA in HSC activation (Supplementary Fig

Cytotoxicity assays of RH-PLGA/chitosan nanoparticles using peripheral blood mononuclear cells and Raw 264.7 macrophages showed IC50 values of 1414 g/mL and 19.3 g/mL, respectively

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Hagleitner, M

When one enzyme, specifically KLK5, is present at high concentrations, inflammatory skin processes begin, including the development of rosacea

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