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Additionally, our transmission electron microscopy (TEM) observations align with this model: as lipid-soluble compounds, ARTs (e.g., DHA) can enter lipid droplets within the parasitic digestive vacuolea phenomenon consistent with prior studies [33]and disrupt the regular agregation of heme into hemozoin crystals

[DOI] [PubMed] [Google Scholar] 195.Min S., Xu J., Ren C., Cai Z., Li H., Wang Z

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E may be the key driver of this phenomenon

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Liposomal formulations, reduced glutathione variants, and alternative delivery routes (IV, intramuscular, nebulized) bypass this limitation but require clinical administration