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A compound called homocysteine thiolactone forms when homocysteine incorrectly binds to lysine residues of cellular proteins, leading to damage in the cell structure

55 The newly synthesized BMP-7, but not BMP-4, activates p-Smad1/5, subsequently inducing the expression of the chondrocyte-specific transcription factor Sox9

Weekly 25 g kg 1 Pb exposure with human body weight is considered the threshold level [22]

Additionally, the development of biomaterials that can release angiogenic factors in a controlled manner is being explored to enhance bone regeneration and repair in orthopedic applications (74)

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[DOI] [PMC free article] [PubMed] [Google Scholar] 130.Wang Y., Jiang Z.M., Nolan M.T., Jiang H., Han H.R., Yu K., Li H.L., Jie B., Liang X.K