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It crosses into the brain and acts as a calming, relaxing neurotransmitter

mTORC1 and mTORC2 converge on the arp2/3 complex to promote kras(g12d)-induced acinar-to-ductal metaplasia and early pancreatic carcinogenesis

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[DOI] [PubMed] [Google Scholar] [221].Leong ML, Gu M, Speltz-Paiz R, Stahura EI, Mottey N, Steer CJ, Wessendorf M, Neuronal loss in the rostral ventromedial medulla in a rat model of neuropathic pain, J Neurosci 31(47) (2011) 1702839