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evaluated the protective role of melatonin against colistin-induced nephrotoxicity through biochemical, histopathological and pharmacokinetic studies in an animal model.112 In preliminary studies, they determined the nephrotoxic potential of four different regimens of colistin to benchmark the regimen for reproducible nephrotoxicity

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Add-on certification options beyond baseline accreditation could attest to a clinical trial sites unique expertise and ability to conduct research in a particular therapeutic area or patient population