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Genetically susceptible individuals often harbor polymorphisms or mutations in key antioxidant defense genes, such as superoxide dismutase, catalase, and glutathione peroxidase, which are essential for neutralizing ROS and preventing oxidative damage (Carmo et al., 2022)

Antioxidant components of naturally-occurring oils exhibit marked anti-inflammatory activity in epithelial cells of the human upper respiratory system

Addition of extra heme increases the intensity of the A 410 signal indicating greater heme occupancy

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153,154 It hosts numerous phosphorylation sites across its N-terminal region, C-terminal region, and repeat region, which are regulated by a balance of various kinases and phosphatases to maintain normal neuronal physiological functions

This hypothesis was tested in several studies exploring the potential of combined therapies of PDEi with classical cytotoxic agents