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In Alzheimer's disease, the iron toxicity accumulation and phospholipid peroxidation are linked to neuronal death [137], while in cardiovascular diseases, ferroptosis can result in endothelial dysfunction and atherosclerosis [138]

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Furthermore, the decrease of intracellular glutathione levels was also observed in T cells cocultured with dendritic cells or fibroblasts pretreated with sulfasalazine (Supplemental Figure 11)

Storage duration after reconstitution depends on solvent composition and study design

Collateral sensitivity of MDR cells to Q4 has been shown to result from the inadvertent depletion of intracellular iron pools, caused by the ABCB1-mediated efflux of Q4-iron complexes

Iqbal, L