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Description
Despite their potential toxicity, O 2 and some of its derivatives, especially H 2 O 2 , are also signaling molecules that mediate a variety of biological responses such as cell proliferation, differentiation, and migration (Holmstrm and Finkel, 2014)
Despite wide dose ranges tested (6 g/kg to 20 mg/kg), multiple administration routes (intramuscular, intraperitoneal, intravenous, oral), and varied dosing frequencies across numerous animal models, no acute lethal dose has been identified
10.1515/dmpt-2018-0040 88 Moreno-FernandezM

nor was it revealing as a prognostic indicator of disease manifestations

Neurogenesis in the adult is involved in the formation of trace memories

Local-tolerance testing revealed only mild irritation at injection sites, and animals showed recovery after treatment-withdrawal periods
