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Epidural anesthesia combined with general anesthesia, for example, has a reduced impact on CD8 + lymphocyte function compared with general anesthesia alone [52]

*Correspondence: Kristine Salma-Ancane, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

The hydroxyl groups on the terminal rings can also form mono- or diester derivatives with fatty acids, which are the predominant forms in many natural sources and further contribute to the diversity of astaxanthin compounds observed in biological systems (Nishida et al., 2023