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An individuals TMAO productivity was determined by calculating the AUC of the OCCT curve (OCCT TMAO AUC ) or by using the OCCT TMAO MAX level

Experiments have demonstrated that the rate of carnitine biosynthesis in the kidneys of vitamin C-deficient guinea pigs decreases by 8 to 10 times, with the heart and skeletal muscle being particularly sensitive to this deficiency

Increased ALOX5 expression elevated leukotriene B4 levels, promoted M1 macrophage polarization, and worsened cardiac injury, whereas ALOX5 knockout or pharmacological inhibition with zileuton reduced inflammation, preserved cardiac function, and improved survival (Xie et al., 2021)

Molecular Pharmacology, 70(5), 1602-1611

Ers antioxidns hatssal rendelkezik, cskkenti a gyulladst , emellett megvja az energiaraktrakat a kirlstl s segt az izomtmeg megrzsben (anti-katabolikus hats)