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The surgery is performed under anaesthesia, while the surgeon identifies the edges of the defect and bring them together permanently using either suture or mesh

Medications Antipsychotic drugs: Some atypical antipsychotics are used to treat irritability and behavioral problems, such as aggression, self-injury, and rapid mood swings

The DNA damage response which consists of the activation of checkpoint pathways, cell cycle arrest and DNA repair, removes most of ROS-induced DNA damage [48]