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Some patients experience headache, others may feel nauseated

But the patient should know the combination has no trial data behind it, the additional cost is real, and the marginal benefit is unproven

You may consider clinical assessment if: Pigmentation is long-standing or resistant to topical care Melasma remains persistent despite conservative management Post-inflammatory hyperpigmentation does not gradually fade Sun damage is extensive Treatment recommendations should always be individualised after medical evaluation

Results Will Begin To Develop 2 Weeks Out Results Start to Appear Around 2 Weeks Out, and Improve Over the Next Couple of Months Patients will see their skin appear more hydrated almost immediately, but the results from the antioxidants and brightening serums take a bit longer to develop