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demonstrated that EGLN3 (egl-9 family hypoxia-inducible factor 3 gene) and c-Myc activate Lyme-specific helicase (LSH) in lung cancer by inhibiting HIF-1 (hypoxia-inducible factor-1) [79]

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The role of mechanotransduction of the high venous pressure in the pathogenesis of varicose vein formation has not been adequately investigated despite a good progress in understanding the mechanomolecular mechanisms involved in transduction of high blood pressure in the arterial wall

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The study also reassessed a subset of patients after initiating a GFD, showing that metabolic profiles, including AA levels, tended to normalize with dietary treatment