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Thiamine is taken up in the small intestine by the THTR1 and THTR2 transporters, which are encoded by the SLC19A2 and SLC19A3 genes and belong to the solute carrier (SLC) family [28]

However, despite these advancements, a significant challenge that persists is the subset of patients who are resistant to or have limited response to immunotherapy (170), particularly in patients with low tumor mutational burden and immunogenic neoantigens (171, 172)

Each batch is subjected to rigorous testing to confirm the exact amino-acid sequence and guarantee a level of purity that meets the demanding standards of the research community

Vitale, L

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