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37 Mice with disrupted CXCR4 receptors experience a rise in endogenous production of ROS, which activates p38 mitogen-activated protein kinases (MAPK), triggers an increase in DNA double-strand breaks, and leads to apoptosis

Extending Serum Half-life of Albumin by Engineering Neonatal Fc Receptor (FcRn) Binding

10.1038/jcbfm.2011.75 93 LieuC

Kuo CS, Chen CY, Huang HL, Tsai HY, Chou RH, Wei JH, et al

& Hochstein, P

Age-related decline in gastric acid production and intrinsic factor availability may reduce the bodys ability to absorb oral B12 and other nutrients, making IM delivery a practical alternative
