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This systematic approach will determine the safety margins and allow researchers to adopt responsible dosing regimens as the peptide finds its place in both lab and emerging clinical applications

For this reason, we are utilizing 15 different iPSC lines in these studies to ensure reproducibility of the two differentiation protocols across multiple lines

10.1016/j.neuron.2012.08.019 Neuron 88 HauptS.EcksteinM.WolfA.ZimmerR.WachsmuthN.MoserO

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These pale areas were present even outside the area that was ligated, and many gross mucosal defects were present in the enlarged colon segment (Table 2, Figure 20)