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The interaction between antioxidants and enzymes plays a vital role in the defense system against oxidative damage

PLoS One (2017) 12(6):e0179363.10.1371/journal.pone.0179363 33 LiuYYangLAnHChangYZhangWZhuYet alHigh expression of Solute Carrier Family 1, member 5 (SLC1A5) is associated with poor prognosis in clear-cell renal cell carcinoma

Chemico-Biological Interactions, 363 , 110019

flow rate 25 mL/min) to obtain BSO-OxOAc (40 mg, 58%) as a white solid

There has been some support for the idea that Bcl-2 along with the 2-oxoglutarate carrier function as GSH transporters, based on correlations between Bcl-2 expression and nuclear GSH levels in cancer, however, this idea has been abandoned since the 2-oxoglutarate carrier has been refuted as a GSH transporter [76,78]

The inhibition affects, inter alia , calcium homeostasis, cell signalling and cell bioenergetics