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doi:10.1016/j.bcp.2008.10.020

Telomerase activity in melanocytic lesions: A potential marker of tumor biology

Phenotypes have been correlated with specific genetic linkage patterns, suggesting a possible correlation

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Apoptotic cells were quantified across different fields of view at 200 magnification utilizing a confocal fluorescence microscope (K1-Fluo) and quantitative analysis of the fluorescence signals was performed using ImageJ software (version 1.34, NIH, Analysis of neurite outgrowth MPG and DRG tissues were collected and preserved according to an established protocol 4,26

We propose a cellular model of CVS in which an aberrant ion gradient begets mitochondrial dysfunction which begets further anomalous ion gradients, etc., forming a pathogenic vicious cycle leading to cellular hyperexcitability (Figure 1)