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For individuals with serum vitamin B12 levels below approximately 358.7 pg/mL, targeted vitamin B12 supplementation may help optimize pregnancy outcomes by regulating one-carbon metabolism and mitigating homocysteine-associated toxicity

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Humans obtain ERG from their diet and accumulate it in various cells and tissues (e.g., kidney, liver, central nervous system, and red blood cells) at high concentrations (100 M to 2 mM) through a highly specific ERG transporter, organic cation/carnitine transporter 1 (OCTN1) 7

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Hagglof C, Hammarsten P, Josefsson A, Stattin P, Paulsson J, Bergh A et al