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Theres one very important exception to that rule: Vitamin A is teratogenic, which means it can cause fetal development issues

Frequency: Treatment protocols can vary, but injections are often administered several times per week initially, with maintenance doses as needed

Neuroimaging findings and clinical evaluation were critical in establishing the diagnosis

Primary resistance is thought to stem from pre-existing heterogeneity within a tumor: rare subpopulations or stress-tolerant cells that harbor survival advantages can survive first-line therapy

[PubMed: 2167514] 649

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