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[DOI] [PubMed] [Google Scholar] 142.Vernimmen D, Marques-Kranc F, Sharpe JA, Sloane-Stanley JA, Wood WG, Wallace HA, Smith AJ, Higgs DR

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These findings indicate that ferroptosis-related genes may act as a prognosis prediction and a target bypass of the conventional treatment

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Mitochondrial DNA (mtDNA), which encodes 13 essential subunits of the electron transport chain (ETC), is particularly susceptible to oxidative stress, resulting in replication errors, point mutations, and large-scale deletions (Robichaux et al., 2023)