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PRP delivers a concentrated burst of growth factors at the injection site, while BPC-157 sustains the angiogenic and healing environment that PRP initiates

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An indwelling cannula causes an immune response that can alter local cytokine production, and thus the resulting cytokine measurements may reflect local artifact rather than systemic change in concentrations (188)

Manifestations of hyperkalemia include: disturbances in cardiac conduction and arrhythmias, including bradycardia, heart block, asystole, ventricular tachycardia, ventricular fibrillation

To evaluate patient-reported effects of treatments, we defined a NAS based on patients responses on the impact of each treatment on their overall condition: The number of positive and negative feedback corresponds to patients reporting any level of improvement or worsening, respectively

Data availability The datasets used and analyzed in this study are available from the corresponding author