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Role of arrestins in OR regulation From the canonical model of GPCR regulation by Lefkowitz, arrestins (arrestins 2 and 3 also named -arrestins 1 and 2, respectively) play a pivotal role in receptor regulation by promoting G protein uncoupling and receptor endocytosis (Pierce et al., 2002)

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References 1 Current Pharmaceutical Design (PubMed)Sikiri P, et al

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