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This section delves into two significant aspects of aerobic exercise's neuroprotective mechanisms: its impact on oxidative stress and its relationship with neurotrophic factors

To assess the antioxidant capacity of CeO 2 @H-151 nanozymes in IR-induced LECs damage, we first measured intracellular ROS levels using the 2,7-dichlorodihydrofluorescein diacetate (DCFH-DA) assay

Thus, although the combination of anti-complement therapies with other anti-cancer agents should be further investigated, the increasing number of studies that demonstrate the improved antitumor responses obtained combining complement inhibitionand in particular C5aR1 inhibitionwith chemotherapy and/or immunotherapy, together with our present results on paclitaxel-mediated C5aR1 activation, further sustain that a combined treatment with paclitaxel and C5aR1 inhibitors could be a promising therapeutic approach, not only to prevent CIPN and HSRs, but also to potentially obtain a synergistic effect on tumor progression

They tested the formulations in vitro by assessing the bioavailability of ingested curcumin

Inflammasomes: Mechanism of assembly, regulation and signalling

Genes & Dis 10(4):13671401 Andreyev J, Ross P, Donnellan C, Lennan E, Leonard P, Waters C et al (2014) Guidance on the management of diarrhoea during cancer chemotherapy