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Although the precise pathogenesis of ASD remains unclear, factors such as genetic predisposition, environmental exposures, immune dysregulation, and neurodevelopmental abnormalities are collectively believed to contribute to its onset

This is in agreement with our recent report that the majority of markers of dysmetabolism manifest early during cardiometabolic disease development 31

In a rat experiment, hydergine regulated the release of the neurotransmitter acetylcholine from the hippocampus [146] and increased the number of cholinergic receptors [147]

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LC is a necessary cofactor in lipid metabolism and, as a result, in the production of cellular energy
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