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These results suggest that the kavalactone components, rather than other components of the extract, are responsible for the inhibition of CYP450 isozymes

Jakimiuk AJ, Weitsman SR, Brzechffa PR et al

[DOI] [PMC free article] [PubMed] [Google Scholar] 33.Guengerich FP

The Butterfield laboratory reported in 1994 (106) that A40, in the presence of a nonparamagnetic nitrone-based spin trap, phenyl- N - t -butylnitrone (PBN), led to the production of a nitroxide, i.e., a stable free radical that could be detected by electron paramagnetic resonance (EPR) (FIGURE 8)

Nanoparticles for oral delivery: Targeted nanoparticles with peptidic ligands for oral protein delivery

10.1038/s41586-023-06878-9 36 GaoQ.ZhouY.ChenY.HuW.JinW.ZhouC.et al (2025)
