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While increased NOX activity may drive ROS production in the setting of sufficient NADPH stores, other NADPH-independent ROS may represent a more abundant alternative source of oxidative stress in this model of G6PD-d

Effect of sesquiterpene lactones on antioxidant enzymes and some drug-metabolizing enzymes in rat liver and kidney

Backstrom, A., C

Because of the influences of age, gender, and unhealthy lifestyle factors such as tobacco smoking, alcohol abuse, inadequate dietary habits, and lack of physical activity, there is no consensus on what levels constitute hyperhomocysteinemia at the present time
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