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First, the direct molecular interactions between TMAO and PCSK9/APOA4, as well as the reciprocal expressions of APOA4 and PCSK9, require further clarification

L-carnitine can also improve expression of some proinflammatory cytokines including TNF-, IL1-, and IFN-, which increase after radiation (19, 65)

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National Center for Complementary and Integrative Health Web site

However, L-carnitine supplementation ameliorates the accumulation of long chain fatty acid around the mitochondria which could inhibit the mitochondrial membrane depolarization and permeability and ultimately suppresses the cells apoptosis [48, 49]

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