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The accumulation of Kyn may be a result of decreased catabolism by Kyn hydroxylase owing to NADPH dependence of this enzyme (Breton et al
doi: 10.1016/j.biotechadv.2022.107962 235 LalondeM.-E.DurocherY
Circ Res (2022) 131(8):70112
A conscious dog model for assessing the absorption, enterocyte-based metabolism, and intestinal lymphatic transport of halofantrine
Gut 1999
doi: 10.1371/journal.ppat.1004256 27 GammonDBMelloCC
