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Multiple nutritional factors and thyroid disease, with particular reference to autoimmune thyroid disease
This presents with sudden-onset pulmonary edema, hypotension, and a new harsh holosystolic murmur heard best at the cardiac apex with radiation to the axilla

Vitamin Cs Role : As a cofactor for pro-collagen enzymes (prolyl hydroxylase and lysyl hydroxylase), Vitamin C is essential for stabilizing and linking collagen fibers

10.1016/j.ijbiomac.2012.07.019 85 XiongY.ZhongW.LiuJ.ChengB.FanJ.ZhouF.et al (2022)

Overall, using gut microbiome and fecal metabolomics, we identified several gut microbiota and abundant fecal metabolites reversed by LGZG in treating NASH
