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Description
When effects on heart rate variability were fractionated into vagal (parasympathetic) and sympathetic contributions, area 25 inactivation selectively increased cardiac vagal tone

Clinical trials confirmed that AOD-9604 has no negative impact on glucose metabolism, representing a significant safety advantage for individuals with metabolic concerns

PMID 18823031 Manning MC, Chou DK, Murphy BM, Payne RW, Katayama DS

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doi:10.1016/j.exer.2015.04.016 25

For a comparison, see semaglutide vs tirzepatide
