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The brain is particularly vulnerable to oxidative stress due to its high oxygen consumption, abundant polyunsaturated fatty acids, and relatively modest antioxidant defenses compared to other organs [1][2][48]

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L., Schirinzi E., and Siciliano G., Curcumin as an ROS Scavenger in Amyotrophic Lateral Sclerosis, Reactive Oxygen Species 2 (2016): 339354

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panthaica by ultra-high performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry

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Given that hepatic glycine homoeostasis is regulated by Shmt2 (serine hydroxymethyltransferase 2) 87 , these and other studies have focused on the role of Shmt2 in MASLD 86,87,88

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& Proudfoot, N

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EDV, end diastolic volume

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