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Once inflammation decreases, guided exercises help restore mobility, flexibility, and tendon strength, preventing future flare-ups

[DOI] [PubMed] [Google Scholar] [75].Cantuti-Castelvetri L, Fitzner D, Bosch-Queralt M, Weil MT, Su M, Sen P, et al

TGF-, PDGF, EGF, and FGF have been shown to stimulate infiltration of inflammatory cells into the wound space.24 These growth factors induce proliferation of keratinocytes and fibroblasts, lead to new formation of capillaries in the granulation tissue, and modulate extracellular matrix deposition and reconstitution of the injured area.25 The topical application of growth factors was successful in accelerating healing of full-thickness wound in normal mice.8,9 The pentadecapeptide body protective compound (BPC)-157 ( Mr 1419), with the sequence Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val, a 15-amino acid fragment of the BPC peptide in gastric juice, is thought to be essential for BPCs activity and has been fully characterized and investigated

Bearing in mind the various factors shown to be involved in the production of new OLGs and in remyelination failure, several strategies for enhancing spontaneous repair may be considered

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M., Bonanno, R., Lacavalla, M., Aiello, M., Airoldi, D., Amaranto, A., Decimi, G., and Vergata, M