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Description
From a physiological standpoint, LCR serves as a substrate for the enzyme carnitine palmitoyltransferase as well as the synthesis of acetylcarnitine, which is necessary for maintaining a feasible pool of free coenzyme A (CoA), allowing for continuation of pyruvate dehydrogenase complex (PDC) and tricarboxylic acid cycle flux 2

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Fujihara, TJ

236 MAT2A has been proposed as a lethal target in MTAP null tumors

Jama (2005) 293(1):905
